Dynamin 1 anticorps (truncated)
Aperçu rapide pour Dynamin 1 anticorps (truncated) (ABIN2464046)
Antigène
Voir toutes Dynamin 1 (DNM1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- truncated
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Immunogène
- Ni-NTA purified truncated recombinant Dynamin-1 expressed in E. Coli strain BL21 (DE3).
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Isotype
- IgG2a
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Indications d'application
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Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000
Determining optimal working dilutions by titration test. -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Stock
- -20 °C
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Stockage commentaire
- Dynamin-1 monoclonal antibody can be stored at -20 °C, stable for one year.
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- Dynamin 1 (DNM1)
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Autre désignation
- Dynamin-1
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Sujet
- Dynamin-1 (Dyn1), with 864-amino acid protein (about 95 kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation.
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ID gène
- 1759
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UniProt
- Q05193
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Pathways
- Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
Antigène
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