ASPSCR1 anticorps (truncated)
Aperçu rapide pour ASPSCR1 anticorps (truncated) (ABIN2464084)
Antigène
Voir toutes ASPSCR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- truncated
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Purification
- Antibody is purified by protein A affinity chromatography and resuspended in PBS with 0.2%BSA, 0.09% sodium azide.
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Immunogène
- Ni-NTA purified truncated recombinant TUG expressed in E. Coli strain BL21 (DE3).
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Isotype
- IgG1
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Indications d'application
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Western Blot:1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test. -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS containing 0.03 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Stock
- -20 °C
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Stockage commentaire
- Mouse TUG monoclonal antibody can be stored at -20 °C, stable for one year.
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- ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))
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Autre désignation
- TUG
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Sujet
- The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.
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ID gène
- 79058
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UniProt
- Q9BZE9
Antigène
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