DDR1 anticorps (C-Term)

N° du produit ABIN2469321

Cet anticorps anti-DDR1 est un anticorps Lapin Polyclonal détectant DDR1 dans IHC. Adapté pour Humain, Singe, Porc, Roussette (Chauve-souris), Cheval, Boeuf (Vache), Chien, Chimpanzé, Gibbon et Gorilla.

Aperçu rapide pour DDR1 anticorps (C-Term) (ABIN2469321)

Antigène: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Reactivité: Humain, Singe, Porc, Roussette (Chauve-souris), Cheval, Boeuf (Vache), Chien, Chimpanzé, Gibbon, Gorilla

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDR1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-DDR1 anticorps

Épitope: C-Term

Specificité: BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DDR2 (69 % ).

Purification: Immunoaffinity Chromatography

Immunogène: DDR1 antibody was raised against a peptide located near the C-Terminal region of DDR1 (Human).

Information d'application

Indications d'application: DDR1 antibody can be used in ELISA, Western Blot starting at 1 - 2 μg/mL, immunocytochemistry, immunohistochemistry starting at 10 μg/mL, immunoprecipitation starting at 1 - 2 μg/mL, and flow cytometry.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-80 °C

Stockage commentaire: DDR1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Détails sur DDR1

Antigène: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Autre désignation: DDR1

Sujet: DDR1 is a DDR/TKT type protein kinase. DDR1 is activated by various types of collagen, including types I through IV. Binding of collagen to DDR1 protein results in autophosphorylation and a delayed but sustained tyrosine kinase activation. DDR1 may function in cell-to-cell interaction or recognition. At least three mRNA variants, resulting in different protein isoforms of 875, 913 and 919 amino acids, have been reported. DDR1 protein has been shown to be over expressed in human breast, ovarian, esophageal and pediatric brain tumors.

ID gène: 780

UniProt: Q08345

Pathways: Signalisation RTK, Smooth Muscle Cell Migration