DDR1 anticorps (N-Term)

N° du produit ABIN2469359

Détail du produit anti-DDR1 anticorps

Antigène: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Épitope: N-Term

Reactivité: Humain, Singe, Chimpanzé, Gorilla, Gibbon

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDR1 est non-conjugé

Application: Immunohistochemistry (IHC)

Specificité: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogène: DDR1 antibody was raised against a peptide located in the N-Terminal region of DDR1 (Human).

Information d'application

Indications d'application: DDR1 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 20 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-80 °C

Stockage commentaire: DDR1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Détails sur DDR1

Antigène: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Autre désignation: DDR1 (DDR1 Produits)

Synonymes: anticorps CG11573, anticorps CG13984, anticorps CG13985, anticorps CG33531, anticorps CG9488, anticorps CG9490, anticorps CT33540, anticorps DDR, anticorps Dmel\\CG33531, anticorps Dmel_CG13984, anticorps 6030432F18, anticorps AI323681, anticorps CD167a, anticorps Cak, anticorps Nep, anticorps PTK3A, anticorps CAK, anticorps CD167, anticorps EDDR1, anticorps HGK2, anticorps MCK10, anticorps NEP, anticorps NTRK4, anticorps PTK3, anticorps RTK6, anticorps TRKE, anticorps Drd1, anticorps PTK3D, anticorps Discoidin domain receptor, anticorps discoidin domain receptor family, member 1, anticorps discoidin domain receptor tyrosine kinase 1, anticorps Ddr, anticorps Ddr1, anticorps DDR1

Sujet: DDR1 is a DDR/TKT type protein kinase. DDR1 is activated by various types of collagen, including types I through IV. Binding of collagen to DDR1 protein results in autophosphorylation and a delayed but sustained tyrosine kinase activation. DDR1 may function in cell-to-cell interaction or recognition. At least three mRNA variants, resulting in different protein isoforms of 875, 913 and 919 amino acids, have been reported. DDR1 protein has been shown to be over expressed in human breast, ovarian, esophageal and pediatric brain tumors.

ID gène: 780

UniProt: Q08345

Pathways: Signalisation RTK, Smooth Muscle Cell Migration