BACE1 anticorps (Internal Region)
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- Antigène Voir toutes BACE1 Anticorps
- BACE1 (Beta-secretase 1 (BACE1))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Singe, Porc, Hamster, Roussette (Chauve-souris), Gibbon
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BACE1 est non-conjugé
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Application
- Immunohistochemistry (IHC)
- Specificité
- BLAST analysis of the peptide immunogen showed no homology with other human proteins.
- Purification
- Immunoaffinity Chromatography
- Immunogène
- BACE1 antibody was raised against a peptide located near the internal domain of BACE1 (Human).
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- Indications d'application
- BACE1 antibody can be used in immunohistochemistry starting at 1:50.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, 0.1 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- As with all antibodies avoid freeze/thaw cycles.
- Stock
- 4 °C/-80 °C
- Stockage commentaire
- BACE1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
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- Antigène
- BACE1 (Beta-secretase 1 (BACE1))
- Autre désignation
- BACE1 (BACE1 Produits)
- Synonymes
- anticorps ASP2, anticorps BACE, anticorps HSPC104, anticorps C76936, anticorps Bace, anticorps MGC145931, anticorps BACE1, anticorps zgc:77409, anticorps beta-secretase 1, anticorps beta-site APP cleaving enzyme 1, anticorps beta-site APP-cleaving enzyme 1, anticorps BACE1, anticorps Bace1, anticorps bace1
- Sujet
- Bace 1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
- ID gène
- 23621
- UniProt
- P56817
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