USP18 anticorps (AA 40-49)
Aperçu rapide pour USP18 anticorps (AA 40-49) (ABIN2469597)
Antigène
Voir toutes USP18 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 40-49
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Purification
- Immunoaffinity Chromatography
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Immunogène
- USP18 antibody was raised against amino acids 40 - 49 of USP18 (Human).
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Indications d'application
- USP18 antibody can be used in ELISA starting at 1:10000 - 1:50000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- As with all antibodies avoid freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store USP18 antibody at 4 °C or -20 °C.
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- USP18 (Ubiquitin Specific Peptidase 18 (USP18))
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Autre désignation
- USP18
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Sujet
- UBP43 (also known as ISG43, Ubl thiolesterase 18, ISG15-specific processing protease, 43 kDa ISG15-specific protease, ubiquitin specific protease 18 or USP18) is a member of the deubiquitinating protease family of enzymes, which removes ubiquitin adducts from a broad range of protein substrates. Deletion of the UBP43 gene in mouse leads to a massive increase of ISG15 conjugates in tissues indicating that UBP43 is a major ISG15-specific protease. UBP43 is the first ISG15-specific protease reported. Both ISG15 and UBP43 genes are known to be strongly induced by interferon, genotoxic stress, and viral infection. Thus UBP43 may be necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms.
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ID gène
- 11274
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UniProt
- Q9UMW8
Antigène
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