TMEM123 anticorps (AA 173-188)

N° du produit ABIN2470150

Détail du produit anti-TMEM123 anticorps

Antigène: TMEM123 (Transmembrane Protein 123 (TMEM123))

Épitope: AA 173-188

Reactivité: Humain, Singe, Lapin, Gibbon, Gorilla

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM123 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Protein G Column

Immunogène: TMEM123 antibody was raised against amino acids 173 - 188 of TMEM123 (Human).

Isotype: IgG

Information d'application

Indications d'application: TMEM123 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: TMEM123 antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.

Détails sur TMEM123

Antigène: TMEM123 (Transmembrane Protein 123 (TMEM123))

Autre désignation: TMEM123 (TMEM123 Produits)

Synonymes: anticorps KCT3, anticorps PORIMIN, anticorps PORMIN, anticorps 2310075C12Rik, anticorps RGD1305625, anticorps kct3, anticorps pormin, anticorps porimin, anticorps transmembrane protein 123, anticorps transmembrane protein 123 L homeolog, anticorps TMEM123, anticorps Tmem123, anticorps tmem123.L, anticorps tmem123

Sujet: Porimin was identified by a monoclonal antibody developed by immunizing mice with apoptotic cells. One of these antibodies, designated anti-Porimin (for pro-oncosis receptor inducing membrane injury), was found to directly induce a unique type of cell death in Jurkat cells by binding to a 110- kDa cell surface receptor on Jurkat cells. Anti-Porimin-mediated cell death was preceded by cell aggregation, formation of plasma membrane pores, and the appearance of membrane blebs. More important, these cells show neither DNA fragmentation nor apoptotic bodies, but display lethal damage of the cell membrane.

ID gène: 114908

UniProt: Q8N131

Pathways: Regulation of Cell Size