Cet anticorps Lapin Polyclonal détecte spécifiquement TMEM123 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Singe, Lapin, Gibbon et Gorilla.
TMEM123
Reactivité: Humain, Souris, Rat
WB, FACS, IF (cc), IF (p)
Hôte: Lapin
Polyclonal
Cy5
Indications d'application
TMEM123 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL.
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, 0.05 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
As with all antibodies avoid freeze/thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
TMEM123 antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.
Antigène
TMEM123
(Transmembrane Protein 123 (TMEM123))
Autre désignation
TMEM123
Sujet
Porimin was identified by a monoclonal antibody developed by immunizing mice with apoptotic cells. One of these antibodies, designated anti-Porimin (for pro-oncosis receptor inducing membrane injury), was found to directly induce a unique type of cell death in Jurkat cells by binding to a 110- kDa cell surface receptor on Jurkat cells. Anti-Porimin-mediated cell death was preceded by cell aggregation, formation of plasma membrane pores, and the appearance of membrane blebs. More important, these cells show neither DNA fragmentation nor apoptotic bodies, but display lethal damage of the cell membrane.