PTH1R anticorps (pThr1)

N° du produit ABIN2470513

Cet anticorps Souris Monoclonal détecte spécifiquement PTH1R dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Boeuf (Vache), Porc, Chien, Singe, Cheval, Gibbon, Gorilla et Orang-Utan.

Aperçu rapide pour PTH1R anticorps (pThr1) (ABIN2470513)

Antigène: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Reactivité: Humain, Boeuf (Vache), Porc, Chien, Singe, Cheval, Gibbon, Gorilla, Orang-Utan

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PTH1R est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PTH1R anticorps

Épitope: pThr1

Specificité: Recognizes human PTH/PTHrP receptor, Mr 80kD, and the receptor dimer, Mr 160kD. A faint nonspecific band at 110kD is also detected. This antibody does not detect the PTH2 receptor.

Purification: Protein G Column

Immunogène: PTHR1 monoclonal antibody was raised against a synthetic peptide corresponding to aa 146 - 169 of PTHR1 (Human).

Isotype: IgG1 kappa

Information d'application

Indications d'application: PTHR1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 15 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.6, 0.07 % sodium azide, 30 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Product should be stored long term (months) at -20 °C and short term (weeks) at 4 °C.

Détails sur PTH1R

Antigène: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Autre désignation: PTHR1

Sujet: PTHR1, a Parathyroid Hormone Receptor, mediates PTH-dependent regulation of mineral-ion homeostasis. It also mediates the paracrine action of PTHRP in endochondral bone formation. Mutations in this receptor are responsible for disorders of calcium and bone metabolism such as chondrodysplasia, hypercalcemia, and chronic renal failure. Three promoters, P1, P2, and P3, regulate the expression of PTHR.

ID gène: 5745

UniProt: Q03431

Pathways: Regulation of Carbohydrate Metabolic Process