CDK2 anticorps

N° du produit ABIN2470565

L’anticorps Souris Monoclonal anti-CDK2 a été validé pour WB, IHC, ELISA et IP. Il convient pour détecter CDK2 dans des échantillons de Humain, Souris et Xenopus laevis.

Aperçu rapide pour CDK2 anticorps (ABIN2470565)

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reactivité: Humain, Souris, Xenopus laevis

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Détail du produit anti-CDK2 anticorps

Specificité: Recognizes cdk2, Mr 33kD. Does not cross-react with other cdks.

Purification: Protein G Column

Immunogène: CDK2 monoclonal antibody was raised against recombinant CDK2 (Human).

Isotype: IgG

Information d'application

Indications d'application: CDK2 antibody can be used in immunohistochemistry starting at 10 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05 % sodium azide, before the addition of glycerol to 30 %

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store CDK2 antibody at 4 °C or -20 °C.

Détails sur CDK2

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Autre désignation: CDK2

Sujet: Cyclin-dependent kinase 2 (CDK2), a CDC2/CDK-type protein kinase, regulates cell-cycle transition from G1 to S phase. CDK2 activation requires formation of a heterodimer with cyclin A, D, or E and phosphorylation by CAK. CDK2 inhibition results from association with p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Two alternatively spliced variants and multiple transcription initiation sites have been reported. Inhibition of CDK2 has been suggested to help prevent chemotherapy-induced alopecia in cancer patients.

ID gène: 1017

UniProt: P24941

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA