DUX4 anticorps (C-Term) (FITC)

N° du produit ABIN2482297

L’anticorps Souris Monoclonal anti-DUX4 a été validé pour WB, IHC, IF et ICC. Il convient pour détecter DUX4 dans des échantillons de Humain.

Aperçu rapide pour DUX4 anticorps (C-Term) (FITC) (ABIN2482297)

Antigène: DUX4 (Double Homeobox 4 (DUX4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DUX4 est conjugé à/à la FITC

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: P2B1

Détail du produit anti-DUX4 anticorps (FITC)

Épitope: C-Term

Specificité: Detects ~45 kDa. No cross-reactivity with DUX4c.

Réactivité croisée: Humain, Souris

Purification: Protein G Purified

Immunogène: C-terminal 76 amino acids of DUX4 with glutathione-s-transferase (gst) tag

Isotype: IgG1

Information d'application

Indications d'application:

• WB (1:1000)
• ICC/IF (1:1000)
• optimal dilutions for assays should be determined by the user.

Commentaires:

1 μg/ml of ABIN2482297 was sufficient for detection of DUX4 in 20 μg of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG: HRP as teh secondary.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Conjugated antibodies should be stored at 4°C

Détails sur DUX4

Antigène: DUX4 (Double Homeobox 4 (DUX4))

Autre désignation: DUX4

Sujet: DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1 (1). Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4). In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues (5).

ID gène: 22947

NCBI Accession: NP_149418

UniProt: F5GZ66