P4HB anticorps (AA 52-63) (FITC)

N° du produit ABIN2484903

Cet anticorps Souris Monoclonal détecte spécifiquement P4HB dans WB, IHC, ELISA, IP, IF et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour P4HB anticorps (AA 52-63) (FITC) (ABIN2484903)

Antigène: P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp P4HB est conjugé à/à la FITC

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: 2E7-7

Détail du produit anti-P4HB anticorps (FITC)

Épitope: AA 52-63

Specificité: Detects ~48 kDa.

Réactivité croisée: Humain

Purification: Protein G Purified

Immunogène: Synthesized peptide - 12 amino acids long (ADGEDGQDPHSK) corresponding to residues 52 - 63 of the EndoPDI protein

Isotype: IgG2a

Information d'application

Indications d'application:

• WB (1:200)
• optimal dilutions for assays should be determined by the user.

Commentaires:

1 μg/ml of ABIN2484903 was sufficient for detection of EndoPDI in 20 μg of heat shocked HeLa cell lysate by colorimetric immunoblot analysis using Goat anti -mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Conjugated antibodies should be stored at 4°C

Détails sur P4HB

Antigène: P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

Autre désignation: PDI

Sujet: Endothelial protein disulfide isomerase (EndoPDI) is a thioredoxin member of the protein disulfide isomerase family of chaperones. This enzyme has been localized to the endoplasmic reticulum in primary endothelial cells, but colocalizes with nucleoli in the nuclei of breast, colon, and renal cancer cells. EndoPDI mRNA and protein expression is induced by hypoxia and exhibits a protective effect on endothelial cells during hypoxia (1).

ID gène: 81567

NCBI Accession: NP_001139021

UniProt: Q8NBS9

Pathways: Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism