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SPTBN4 anticorps (AA 1621-1832) (PE)

SPTBN4 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S393-2 PE
N° du produit ABIN2485679
  • Antigène Voir toutes SPTBN4 Anticorps
    SPTBN4 (Spectrin Beta, Non-Erythrocytic 4 (SPTBN4))
    Épitope
    • 11
    • 1
    • 1
    • 1
    • 1
    AA 1621-1832
    Reactivité
    • 15
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 13
    • 1
    • 1
    Souris
    Clonalité
    • 13
    • 2
    Monoclonal
    Conjugué
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SPTBN4 est conjugé à/à la PE
    Application
    • 14
    • 13
    • 13
    • 11
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    Detects ~>200 kDa. Does not cross react with other Beta-spectrins
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Protein G Purified
    Immunogène
    Fusion protein amino acids 1621-1832 (C-terminal repeats 14 to 15) of human Beta4-spectrin
    Clone
    S393-2
    Isotype
    IgG1
    Top Product
    Discover our top product SPTBN4 Anticorps primaire
  • Indications d'application
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    A 1:100 dilution of ABIN2485679 was sufficient for detection of Beta 4 Spectrin in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    SPTBN4 (Spectrin Beta, Non-Erythrocytic 4 (SPTBN4))
    Autre désignation
    beta 4 Spectrin (SPTBN4 Produits)
    Synonymes
    anticorps qv, anticorps dyn, anticorps lnd, anticorps SpbIV, anticorps ROSA62, anticorps nmf261, anticorps nmf379, anticorps 1700022P15Rik, anticorps 5830426A08Rik, anticorps Spnb4, anticorps QV, anticorps SPNB4, anticorps SPTBN3, anticorps spectrin beta, non-erythrocytic 4, anticorps spectrin, beta, non-erythrocytic 4, anticorps Sptbn4, anticorps SPTBN4
    Sujet
    Spectrin is the major constituent of the cytoskeletal network underlying the erthrocyte plasma membrane and determines cell shape, arrangement of transmembrane proteins and organization of organelles. It is expressed at very low levels in many tissues, with the strongest expression in the cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder and heart (1). Spectrin beta 4 is a non-erythrocyte member, and is expressed in the brain and pancreatic islets and localisted to the nuclear matrix, cytoplasmic vesicles and PML nuclear bodies. Beta4 spectrins are also essential for membrane stability and the molecular organization of the nodes of Ranvier (2).
    ID gène
    57731
    NCBI Accession
    NP_066022
    UniProt
    Q9H254
    Pathways
    Sensory Perception of Sound, Regulation of Actin Filament Polymerization, Maintenance of Protein Location
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