Aquaporin 1 anticorps (N-Term) (Atto 390)

N° du produit ABIN2486434

L’anticorps Lapin Polyclonal anti-Aquaporin 1 a été validé pour WB, IHC, IF et ICC. Il convient pour détecter Aquaporin 1 dans des échantillons de Rat.

Aperçu rapide pour Aquaporin 1 anticorps (N-Term) (Atto 390) (ABIN2486434)

Antigène: Aquaporin 1 (AQP1) (Aquaporin 1 (Colton Blood Group) (AQP1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aquaporin 1 est conjugé à/à la Atto 390

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-Aquaporin 1 anticorps (Atto 390)

Épitope: N-Term

Specificité: Detects ~28.5 kDa. May detect larger glycosylated bands ~35-50 kDa.

Réactivité croisée: Humain, Souris, Rat

Purification: Protein A Purified

Immunogène: Produced against the N-terminal peptide (sequence N-MASEFKKKLF) of rat Aquaporin 1

Information d'application

Indications d'application:

• WB (1:2000)
• IHC (1:200)
• ICC/IF (1:400)
• optimal dilutions for assays should be determined by the user.

Commentaires:

0.5 μg/ml of ABIN2486434 was sufficient for detection of aquaporin 1 in 10 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Conjugated antibodies should be stored at 4°C

Détails sur Aquaporin 1

Antigène: Aquaporin 1 (AQP1) (Aquaporin 1 (Colton Blood Group) (AQP1))

Autre désignation: Aquaporin 1

Sujet: Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins (1, 2). Aquarporin 1 is a widely expressed water channel, found in the basolateral and apical plasma membranes of the proximal tubes, the descending loop of Henel and in the descending portion of the vasa recta. Additionally it is found in red blood cells, vascular endothelium, gastrointestinal tract, sweat glands and lungs. It is not regulated by vasopressin (3).

ID gène: 25240

NCBI Accession: NP_036910

UniProt: P29975

Pathways: Hormone Transport