Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2) (AA 20-120) anticorps (HRP)
Aperçu rapide pour Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2) (AA 20-120) anticorps (HRP) (ABIN2559498)
Antigène
Voir toutes Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 20-120
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Réactivité croisée
- Souris
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Homologie
- Human,Rat,Cow,Sheep
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human GRF2
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2)
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Autre désignation
- GRF2
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Sujet
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Synonyms: GRF2, RAS-GRF2, Ras-specific guanine nucleotide-releasing factor 2, Ras guanine nucleotide exchange factor 2, RASGRF2
Background: Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation.
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ID gène
- 5924
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UniProt
- O14827
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Pathways
- Neurotrophin Signaling Pathway
Antigène
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