L’anticorps anti-CD40 Ligand Monoclonal Hamster est utilisé pour la détection de CD40 Ligand dans des échantillons de Souris. Il a été validé pour FACS.
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Antigène
CD40 Ligand (CD40LG)
Autre désignation
CD154
Sujet
The MR1 monoclonal antibody specifically reacts with mouse CD154, a 39kDA transmembrane glycoprotein also known as CD40 ligand and gp39. CD154 is expressed on activated T cells and plays a role in B-T cell costimulation. The interaction of CD154 with CD40 induces B cell cycle entry and the signaling for T-dependent B cell activation. By interfering with this interaction, the MR1 antibody is reported to inhibit T and B lymphocyte activation.