CD40 anticorps

N° du produit ABIN2567689

Cet anticorps anti-CD40 est un anticorps Hamster Monoclonal détectant CD40 dans FACS et Func. Adapté pour Souris et Rat.

Aperçu rapide pour CD40 anticorps (ABIN2567689)

Antigène: CD40

Reactivité: Souris, Rat

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp CD40 est non-conjugé

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: HM40-3

Détail du produit anti-CD40 anticorps

Specificité: The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50.

Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Isotype: IgM kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-buffered aqueous solution, ph7.2.

Stock: 4 °C

Stockage commentaire: The product should be stored undiluted at 4°C. Do not freeze.

Détails sur CD40

Antigène: CD40

Autre désignation: CD40

Sujet: The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.

ID gène: 21939

UniProt: P27512

Pathways: Signalisation NF-kappaB, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints