Integrin beta 3 anticorps
Aperçu rapide pour Integrin beta 3 anticorps (ABIN2567868)
Antigène
Voir toutes Integrin beta 3 (ITGB3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The VI-PL2 monoclonal antibody reacts with CD61, a type I integral transmembrane glycoprotein also known as integrin beta 3.
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Purification
- The monoclonal antibody was purified utilizing affinity chromatography.
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Isotype
- IgG1 kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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Stock
- 4 °C
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Stockage commentaire
- The product should be stored undiluted at 4°C. Do not freeze.
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- Integrin beta 3 (ITGB3)
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Autre désignation
- CD61
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Sujet
- The VI-PL2 monoclonal antibody reacts with CD61, a type I integral transmembrane glycoprotein also known as integrin beta 3. CD61 forms a complex with CD41 (platelet gpIIb) and CD51 (integrin alphaV). It is expressed on osteoclasts, fibroblasts, platelets, macrophages, and megakaryocytes and appears to bind to fibronectin, vitronectin, thrombospondin, and fibrinogen and vWF. The VI-PL2 antibody is reported to be cross-reactive with baboon, rhesus, and cynomolgus.
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ID gène
- 3690
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UniProt
- P05106
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
Antigène
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