CD8 alpha anticorps (APC)
Aperçu rapide pour CD8 alpha anticorps (APC) (ABIN2567981)
Antigène
Voir toutes CD8 alpha (CD8A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The 2.43 monoclonal antibody specifically reacts with mouse CD8 antigen.
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Purification
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Isotype
- IgG2b
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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Stock
- 4 °C
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Stockage commentaire
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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Autre désignation
- CD8a
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Sujet
- The 2.43 monoclonal antibody specifically reacts with mouse CD8 antigen. CD8a (the alpha chains) form heterodimers with CD8b (the beta chains) or homodimers (alpha-alpha), which occur as receptors on the surface of the majority of thymocytes. A subpopulation of mature T lymphocytes expresses the CD8 alpha beta (alpha beta TCR T cells), and a subpopulation of intestinal intraepithelial lymphocytes and dendritic cells express CD8a without CD8b. CD8 interacts with the mouse major histocompatibility complex class I (MHC class I) molecules on antigen-presenting cells or epithelial cells.
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ID gène
- 12525
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UniProt
- P01731
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Pathways
- TCR Signaling
Antigène
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