TAL1 anticorps (pSer122)

N° du produit ABIN2568468

Détail du produit anti-TAL1 anticorps

Antigène: TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))

Épitope: pSer122

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAL1 est non-conjugé

Application: Western Blotting (WB)

Specificité: The antibody detects endogenous levels of TAL-1 only when phosphorylated at serine 122.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: TAL-1 (phospho Ser122) antibody was raised against a peptide sequence around phosphorylation site of Serine 122 (Q-L-S (p)-P-P) derived from Human TAL-1.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur TAL1

Antigène: TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))

Autre désignation: TAL-1 (TAL1 Produits)

Synonymes: anticorps SCL/tal-1, anticorps Scl, anticorps bHLHa17, anticorps tal-1, anticorps SCL, anticorps TCL5, anticorps scl, anticorps tcl5, anticorps SCL-alpha, anticorps SCL-beta, anticorps scl/tal1, anticorps zgc:85605, anticorps T cell acute lymphocytic leukemia 1, anticorps TAL bHLH transcription factor 1, erythroid differentiation factor, anticorps T-cell acute lymphocytic leukemia 1 S homeolog, anticorps T-cell acute lymphocytic leukemia 1, anticorps Tal1, anticorps TAL1, anticorps tal1.S, anticorps tal1

Sujet: TAL-1 is a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2.

Poids moléculaire: 45 kDa

ID gène: 6886

NCBI Accession: NP_001274276

UniProt: P17542

Pathways: Stem Cell Maintenance