tau anticorps (pSer202, pSer519)

N° du produit ABIN2568469

Cet anticorps anti-tau Polyclonal Lapin (ABIN2568469) détecte spécifiquement tau dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour tau anticorps (pSer202, pSer519) (ABIN2568469)

Antigène: tau (tau Protein)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp tau est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-tau anticorps

Épitope: pSer202, pSer519

Specificité: The antibody detects endogenous levels of Tau only when phosphorylated at serine 519/202.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: Tau (phospho Ser519/202) antibody was raised against a peptide sequence around phosphorylation site of Serine 519/202 (P-G-S (p)-P-G) derived from Human Tau.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur tau

Antigène: tau (tau Protein)

Autre désignation: tau

Sujet: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Poids moléculaire: 85 kDa

ID gène: 4137

NCBI Accession: NP_058519

UniProt: P10636