PAI1 anticorps
Aperçu rapide pour PAI1 anticorps (ABIN264029)
Antigène
Voir toutes PAI1 (SERPINE1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Attributs du produit
- Synonyms: Serpin E1, PLANH1, Plasminogen Activator Inhibitor 1, PAI-1, PAI, Endothelial plasminogenactivator inhibitor
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Purification
- Protein A chromatography
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Pureté
- > 98 % pure (SDS-PAGE)
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Immunogène
- Recombinant human PAI
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Isotype
- IgG
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Indications d'application
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 2.5mg/mL (OD280nm, E0.1% = 1.36)
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Buffer
- 0.05 M Sodium phosphate, 0.5 M Sodium chloride, 1 mM EDTA, pH 6.6
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Stock
- -80 °C
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Stockage commentaire
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Store the antibody at -70 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
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Autre désignation
- SERPINE1 / PAI1
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Sujet
- PAI1 (plasminogen activator inhibitor 1) is originally cloned from human endothelial cell (Pannekoek 1986, Ginsburg 1986) and rat hepatoma cell 3 cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI1 inhibits both tissue type plasminogen activator (tPA) and urokinase type plasminogen activator (uPA). High PAI1 levels are associated with an increased risk of thromboembolic disease while PAI1 deficiency may represent an inherited autosomal recessive bleeding disorder.Synonyms: Endothelial plasminogen activator inhibitor, PAI, PAI-1, PLANH1, Plasminogen Activator Inhibitor 1, Serpin E1
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UniProt
- P05121
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Pathways
- Signalisation p53, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
Antigène
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