p107 anticorps (N-Term)

N° du produit ABIN264368

L’anticorps Souris Monoclonal anti-p107 a été validé pour WB. Il convient pour détecter p107 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour p107 anticorps (N-Term) (ABIN264368)

Antigène: p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp p107 est non-conjugé

Application: Western Blotting (WB)

Clone: KAB6

Détail du produit anti-p107 anticorps

Épitope: N-Term

Attributs du produit: Synonyms: Retinoblastoma-like protein 1, 107 kDa retinoblastoma-associated protein, p107, pRb1

Purification: Protein A/G chromatography

Pureté: > 95 % by SDS-PAGE

Immunogène: GST fusion protein to the N terminus of p107. Genename: RBL1

Isotype: IgG1

Information d'application

Indications d'application: Suitable for Western Blots at 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.08 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Date de péremption: 12 months

Détails sur p107

Antigène: p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

Autre désignation: RBL1

Sujet: P107 is related both in structure and function to the retinoblastoma tumor suppressor protein and p130 (collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p107 converts E2F transcription factors from transcriptional activators to transcriptional repressors.Synonyms: 107 kDa retinoblastoma-associated protein, Retinoblastoma-like protein 1, p107, pRb1

UniProt: P28749

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases