p130 anticorps (N-Term)
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- Antigène Voir toutes p130 (RBL2) Anticorps
- p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
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Épitope
- N-Term
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Reactivité
- Humain, Rat, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp p130 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130 kDa.
- Attributs du produit
- Synonyms: Retinoblastoma-like protein 2, RB2, 130 kDa retinoblastoma-associated protein, p130,Retinoblastoma-related protein 2, RBR-2, pRb2
- Purification
- Protein A/G chromatography.
- Immunogène
- GST fusion protein to the N terminus of p130.
- Clone
- KAB40
- Isotype
- IgG1
- Top Product
- Discover our top product RBL2 Anticorps primaire
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- Indications d'application
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Suitable for Western Blots at 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.08 % Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch - Date de péremption
- 12 months
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- Antigène
- p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
- Autre désignation
- RBL2 / p130 (RBL2 Produits)
- Synonymes
- anticorps RBL2, anticorps RBR2, anticorps RRB2a, anticorps PRB2, anticorps RBR-2, anticorps Rb2, anticorps p130, anticorps P130, anticorps retinoblastoma-like 2 (p130), anticorps RB transcriptional corepressor like 2, anticorps related to retinoblastoma 2, anticorps RBL2, anticorps LOC541652, anticorps Rbl2
- Sujet
- P130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107 (collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors.Synonyms: 130 kDa retinoblastoma-associated protein, RB2, RBR-2, Retinoblastoma-like protein 2, Retinoblastoma-related protein 2, p130, pRb2
- ID gène
- 5934
- UniProt
- Q08999
- Pathways
- Cycle Cellulaire, Mitotic G1-G1/S Phases
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