Retinoblastoma 1 anticorps (AA 300-380)

N° du produit ABIN264374

L’anticorps anti-Retinoblastoma 1 Monoclonal Souris est utilisé pour la détection de Retinoblastoma 1 dans des échantillons de Humain, Souris, Rat et Poulet. Il a été validé pour IP.

Aperçu rapide pour Retinoblastoma 1 anticorps (AA 300-380) (ABIN264374)

Antigène: Retinoblastoma 1 (RB1)

Reactivité: Humain, Souris, Rat, Poulet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoblastoma 1 est non-conjugé

Application: Immunoprecipitation (IP)

Clone: C36

Détail du produit anti-Retinoblastoma 1 anticorps

Épitope: AA 300-380

Specificité: Retinoblastoma binds and regulates E2F transcription factors.

Attributs du produit: Synonyms: Retinoblastoma 1, Rb, p105-Rb, pRb, pp110, OSRC

Purification: From ascites.

Immunogène: Recombinant protein corresponding to amino acids 300 to 380 of the humanretinoblastoma sequence.

Isotype: IgG1

Information d'application

Indications d'application: Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.08 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Date de péremption: 12 months

Détails sur Retinoblastoma 1

Antigène: Retinoblastoma 1 (RB1)

Autre désignation: Retinoblastoma-Associated Protein / RB1

Sujet: Retinoblastoma encodes a phosphorylated protein p110 and binds and regulates E2F transcription factors. Rb functions as a major cell cycle regulator by its ability to repress gene transcription by all three RNA polymerases. In its hypophosphorylated form, Rb binds to a subset of E2F containing complexes converting them to repressors preventing expression of E2F target genes. These complexes repress transcription via E2F binding elements in the promotersof cell cycle control genes, such as E2F-1, c-myc, and cdc2 genes.Synonyms: OSRC, Rb, Retinoblastoma 1, p105-Rb, pRb, pp110

ID gène: 5925

UniProt: P06400

Pathways: Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy