LEF1 anticorps (all Isoforms)
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- Antigène Voir toutes LEF1 Anticorps
- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
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Épitope
- all Isoforms
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp LEF1 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody detects all LEF-1 isoforms by Western blot and does not cross-react with TCF-1 or TCF-4. Recognizes an epitope in amino acids 256-308 of LEF-1. This region is between the transactivation domain and the HMG binding domain of LEF-1 and is conserved in all LEF-1 isoforms.
- Attributs du produit
- Synonyms: Lymphoid enhancer-binding factor 1, LEF-1, T cell-specific transcription factor 1-alpha,TCF1-alpha
- Purification
- Purified
- Immunogène
- Recombinant full length LEF-1 protein. Genename: LEF1
- Clone
- 1C3-1D10
- Isotype
- IgG1
- Top Product
- Discover our top product LEF1 Anticorps primaire
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- Indications d'application
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Suitable for use in Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.08 % Sodium Azide as preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch - Date de péremption
- 12 months
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- Antigène
- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
- Autre désignation
- LEF1 (LEF1 Produits)
- Synonymes
- anticorps LEF1, anticorps 3000002B05, anticorps AI451430, anticorps Lef-1, anticorps LEF-1, anticorps TCF10, anticorps TCF1ALPHA, anticorps TCF7L3, anticorps lymphoid enhancer binding factor 1, anticorps lymphoid enhancer-binding factor 1, anticorps lymphoid enhancer factor XLEF-1B, anticorps LEF1, anticorps lef1, anticorps Lef1
- Sujet
- Lymphoid Enhancer Factor-1 (LEF-1) is an HMG 1/2-like DNA binding/bending protein and is a member of the LEF/TCF transcription factor family. There are four LEF/TCF family members in mammalian systems (LEF-1, TCF-1, TCF-3 and TCF-4), and orthologs to these factors have been identified in many different species. LEF/TCFs are downstream mediators of Wnt/Wingless signals. Wnt signaling drives cell polarity, cell fate and cell growth decisions in embryonic tissues and in post-natal tissues that continue to develop from mitotically active stem cell precursors. Misregulation of Wnt signaling is also implicated as a root cause of many different cancers, such as colon cancer, melanoma, breast cancer, prostate cancer and others.Synonyms: LEF-1, Lymphoid enhancer-binding factor 1, T cell-specific transcription factor 1-alpha, TCF1-alpha
- ID gène
- 51176
- UniProt
- Q9UJU2
- Pathways
- Signalisation WNT, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
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