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MMP2 anticorps (C-Term)

Cet anticorps Souris Monoclonal détecte spécifiquement MMP2 dans WB, IHC (fro) et EIA. Il présente une réactivité envers Humain.
N° du produit ABIN264505

Aperçu rapide pour MMP2 anticorps (C-Term) (ABIN264505)

Antigène

Voir toutes MMP2 Anticorps
MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reactivité

  • 158
  • 83
  • 71
  • 53
  • 8
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
Humain

Hôte

  • 132
  • 49
  • 1
Souris

Clonalité

  • 127
  • 55
Monoclonal

Conjugué

  • 92
  • 14
  • 13
  • 9
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp MMP2 est non-conjugé

Application

  • 149
  • 55
  • 54
  • 49
  • 39
  • 39
  • 31
  • 27
  • 26
  • 24
  • 17
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone

4D3
  • Épitope

    • 16
    • 16
    • 16
    • 12
    • 10
    • 9
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Specificité

    This antibody reacts to Matrix Metalloproteinase 2.

    Attributs du produit

    Synonyms: MMP2, CLG4A, 72 kDa gelatinase, Matrix metalloproteinase-2, Gelatinase A, TBE-1, 72 kDatype IV collagenase

    Purification

    Purified

    Immunogène

    Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with asynthetic peptide derived from the Cterminus of the human MMP2 protein and mousemyeloma Ag8563 cells.

    Isotype

    IgG1
  • Indications d'application

    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections: 1 - 5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Buffer

    Phosphate buffered saline with 0.08 % sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    Date de péremption

    12 months
  • Antigène

    MMP2 (Matrix Metalloproteinase 2 (MMP2))

    Autre désignation

    MMP-2

    Sujet

    The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves Collagen Types IV, V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.Synonyms: 72 kDa gelatinase, 72 kDa type IV collagenase, CLG4A, Gelatinase A, MMP2, Matrix metalloproteinase-2, TBE-1

    ID gène

    4313

    UniProt

    P08253

    Pathways

    Activation of Innate immune Response
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