SERPINC1 anticorps

N° du produit ABIN264614

L’anticorps Mouton Polyclonal anti-SERPINC1 a été validé pour IHC (p) et ID. Il convient pour détecter SERPINC1 dans des échantillons de Humain, Souris, Rat, Chien, Cheval et Cat.

Aperçu rapide pour SERPINC1 anticorps (ABIN264614)

Antigène: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Cat

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp SERPINC1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunodiffusion (ID)

Détail du produit anti-SERPINC1 anticorps

Specificité: Antibody to Human Antithrombin III. This Antithrombin III antibody gives a single arc when tested by IEP against human plasma. Identity is confirmed by double diffusion (Ouchterlony) against human plasma and a known anti-human antithrombin III. The cross reactivity of this product against the sera of the species listed below has been assessed by double diffusion using 10 μL of antisera against 5 μL of species sera. These results are intended as a guideline only.

Purification: Ion Exchange Chromatography (DEAE); immunoelectrophoresis (IEP) and double diffusion

Immunogène: Human Antithrombin III purified from plasma, shown to be homogeneous by SDS-PAGE.

Information d'application

Indications d'application: RID: 6l antiserum / cm2 gel vs.5 μL neat - 1/10 dilution human plasma. Double Diffusion: 10l antiserum vs.5l plasma. IEP: 100l antiserum vs.5l plasma. The use of 3 % PEG 6000 with 1.2 % agarose in a suitable buffer (such as TBE or Tris-barbital pH >8.2) is recommended.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 11.0 mg/mL (OD280nm, E1% = 14.5)

Buffer: Glycine buffered saline, pH 7.4 containing 0.099 % Sodium Azide, 0.1 % EACA, 0.01 % Benzamidine, 1 mM EDTA

Agent conservateur: Sodium azide, Benzamidine, EACA

Précaution d'utilisation: This product contains Sodium azide, Benzamidine and EACA: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur SERPINC1

Antigène: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Autre désignation: SERPINC1 / Antithrombin-III

Sujet: Antithrombin III (ATH III) is a plasma protein synthesised in the liver. Normal plasma levels are 115 to 160 mg/L. ATH III consists of a single polypeptide chain and has a molecular weight of 58 kDa. ATH III is a serine protease inhibitor and regulates coagulation by the formation of covalently liked complexes. ATH III also has a heparin binding site and in the presence of heparin the inhibition of thrombin, factors IXa, Xa and XIa is enhanced 1000 fold. Low levels of ATH III (functional or concentration) are associated with deep vein thrombosis and pulmonary embolism. Antithrombin assays are based on immunologic, enzymatic, or clotting properties.Synonyms: AT3, ATIII, Serpin C1

ID gène: 462

NCBI Accession: NP_000479

UniProt: P01008