EPH Receptor B1 anticorps

N° du produit ABIN264960

Cet anticorps anti-EPH Receptor B1 Polyclonal Mouton (ABIN264960) détecte spécifiquement EPH Receptor B1 dans IP. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour EPH Receptor B1 anticorps (ABIN264960)

Antigène: EPH Receptor B1 (EPHB1)

Reactivité: Humain

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor B1 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-EPH Receptor B1 anticorps

Specificité: This antibody reacts to ephB1 (Elk receptor) - SAM.

Purification: Purified

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1 - 10 μg/mL. Immunoprecipitation: 10 - 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur EPH Receptor B1

Antigène: EPH Receptor B1 (EPHB1)

Autre désignation: EPHB1

Sujet: The immunogen used for the anti-human ephB1 (Elk receptor) -SAM region was a GST fusion protein ephB1 (Elk receptor) -SAM corresponding to amino acid sequence 883 - 984 of the C terminus region and having a molecular weight of 116 kD. ephB1, previously known as Elk (eph-like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. ephB family proteins bind ephrins of the B class, ligands that are also transmembrane spanning proteins capable of transmitting signals. ephB1 is expressed predominantly in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, ephB1 signals regulation of cell attachment and cellcell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.Synonyms: ELK, EPH2, EPHT2, Ephrin type-B receptor 1, HEK6, NET, Tyrosine-protein kinase receptor EPH-2

ID gène: 2047

NCBI Accession: NP_004432

UniProt: P54762

Pathways: Signalisation RTK