BIK anticorps
-
- Antigène Voir toutes BIK Anticorps
- BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp BIK est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Specificité
- The antibody detects endogenous levels of BIK protein (region surrounding Met27).
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen
- Pureté
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product BIK Anticorps primaire
-
-
- Indications d'application
-
ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Antigène
- BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
- Autre désignation
- BIK (BIK Produits)
- Synonymes
- anticorps BIK, anticorps Biklk, anticorps Blk, anticorps Nbk, anticorps BIP1, anticorps BP4, anticorps NBK, anticorps si:dkey-31f5.6, anticorps BCL2 interacting killer, anticorps BCL2-interacting killer, anticorps BCL2-interacting killer (apoptosis-inducing), anticorps BIK, anticorps Bik, anticorps bik
- Sujet
- Bik/Nbk (Bcl-2-interacting killer/natural born killer) is a potent pro-apoptotic protein belonging to a group of Bcl-2 family members that includes Bad, Bid, Bim, Hrk, and Noxa, containing a BH3 domain but lacking other conserved domains, BH1 or BH2. Functionally, Bik is able to bind to and antagonize anti-apoptotic Bcl-2 family members including Bcl-2, Bcl-xL, and viral homologs E1B-19K and EBV-BHFR1. The BH3 domain of Bik is essential for its apoptotic activity and interaction with survival proteins. Phosphorylation of Bik is correlated with an increase in its pro-apoptotic activity.Synonyms: Apoptosis inducer NBK, BIP1, BP4, Bcl-2-interacting killer, NBK
- Poids moléculaire
- approx. 23 kDa
- ID gène
- 638
- NCBI Accession
- NP_001188
- UniProt
- Q13323
- Pathways
- Positive Regulation of Endopeptidase Activity
-