Claudin 11 anticorps

N° du produit ABIN265360

Cet anticorps Lapin Polyclonal détecte spécifiquement Claudin 11 dans WB et EIA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Claudin 11 anticorps (ABIN265360)

Antigène: Claudin 11 (CLDN11)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 11 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-Claudin 11 anticorps

Specificité: This antibody detects endogenous levels of Claudin 11 protein. (region surrounding Ser198)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1: 1000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.3, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Claudin 11

Antigène: Claudin 11 (CLDN11)

Autre désignation: Claudin-11 / CLDN11

Sujet: The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteinsare known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Emerging evidence suggests that the Claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions.Synonyms: OSP, OTM, Oligodendrocyte-specific protein

Poids moléculaire: approx. 24 kDa

ID gène: 5010

NCBI Accession: NP_005593

UniProt: O75508

Pathways: Hepatitis C