MMP1 anticorps

N° du produit ABIN265522

Détail du produit anti-MMP1 anticorps

Antigène: MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: This antibody detects endogenous levels of MMP-1 protein. (region surrounding His440)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur MMP1

Antigène: MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

Autre désignation: MMP-1 (MMP1 Produits)

Synonymes: anticorps CLG, anticorps CLGN, anticorps Mmp1a, anticorps CG4859, anticorps Dm1-MMP, anticorps Dmel\\CG4859, anticorps MMP-1, anticorps MMP1, anticorps Mmp 1, anticorps dMMP1, anticorps dm1-MMP, anticorps dmmp1, anticorps l(2)k04809, anticorps mmp1, anticorps Mmp1, anticorps Mcol-A, anticorps Mcola, anticorps col4, anticorps mmp18, anticorps Clgn, anticorps matrix metallopeptidase 1, anticorps Matrix metalloproteinase 1, anticorps matrix metalloproteinase 1, anticorps matrix metallopeptidase 1 (interstitial collagenase), anticorps matrix metallopeptidase 1a (interstitial collagenase), anticorps matrix metallopeptidase 1 S homeolog, anticorps interstitial collagenase, anticorps matrix metallopeptidase 8 L homeolog, anticorps MMP1, anticorps Mmp1, anticorps RB11133, anticorps Mmp1a, anticorps mmp1.S, anticorps LOC100727966, anticorps mmp8.L

Sujet: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is downregulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression.Synonyms: CLG, Fibroblast collagenase, Interstitial collagenase, MMP1, Matrix metalloproteinase-1

Poids moléculaire: approx. 54 kDa

ID gène: 4312

NCBI Accession: NP_002412

UniProt: P03956