Tissue factor anticorps (APC)

N° du produit ABIN2656923

Détail du produit anti-Tissue factor anticorps (APC)

Antigène: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Tissue factor est conjugé à/à la APC

Application: Western Blotting (WB), ELISA

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Clone: NY2

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détails sur Tissue factor

Antigène: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Autre désignation: CD142 (F3 Produits)

Synonymes: anticorps CD142, anticorps TF, anticorps TFA, anticorps PRO1557, anticorps PRO2086, anticorps TFQTL1, anticorps f3, anticorps AA409063, anticorps Cf-3, anticorps Cf3, anticorps tf, anticorps zgc:112151, anticorps coagulation factor III, tissue factor, anticorps transferrin, anticorps coagulation factor IIIa, anticorps coagulation factor III, anticorps tissue factor, anticorps coagulation factor IIIb, anticorps coagulation factor III (thromboplastin, tissue factor) S homeolog, anticorps F3, anticorps TF, anticorps f3a, anticorps tf, anticorps f3b, anticorps f3.S

Sujet: CD142, also known as Tissue Factor (TF), Coagulation Factor III, and Thromboplastin, is a 45 kD type I transmembrane glycoprotein. It is expressed on the surface of a variety of cells that are physically separated from the circulating blood which include smooth muscle cells, fibroblasts, keratinocytes, glomerular epithelial cells (cytoplasmic inclusions), astrocytes, myocardium, liver stromal cells, pancreas cells, and is also expressed on activated monocytes and stimulated endothelial cells. CD142 is a high-affinity receptor for coagulation factor VII and initiates the extrinsic pathway of blood coagulation. CD142 also plays an important role in a variety of diseases such as sepsis, atherosclerosis, and cancer.

Pathways: Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling