Podoplanin anticorps (Alexa Fluor 488)

N° du produit ABIN2657577

Cet anticorps anti-Podoplanin Monoclonal Rat conjugué à Alexa Fluor 488 (Clone NC-08) (ABIN2657577) détecte spécifiquement Podoplanin dans ICFC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Podoplanin anticorps (Alexa Fluor 488) (ABIN2657577)

Antigène: Podoplanin (PDPN)

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Podoplanin est conjugé à/à la Alexa Fluor 488

Application: Intracellular Flow Cytometry (ICFC)

Clone: NC-08

Détail du produit anti-Podoplanin anticorps (Alexa Fluor 488)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Isotype: IgG2a lambda

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détails sur Podoplanin

Antigène: Podoplanin (PDPN)

Autre désignation: Podoplanin

Sujet: Podoplanin is a 40-43 kD type-I transmembrane sialomucin-type glycoprotein, also known as T1a, gp36, gp38, gp40, and Aggrus. Originally detected on the surface of podocytes, futher characterization showed podoplanin has a broad tissue distribution, including mesothelial cells, epithelial cells, follicular dendritic cells, and a variety of tumor cells. It has been reported that podoplanin is the ligand of CLEC2 and is involved in lymphatic vessel formation, platelet aggregation, and tumor metastasis. Podoplanin may serve as a useful marker for tumor diagnosis and prognosis.

Pathways: Dicarboxylic Acid Transport