SLAMF1 anticorps

N° du produit ABIN2658114

Cet anticorps Rat Monoclonal détecte spécifiquement SLAMF1 dans MA. Il présente une réactivité envers Souris.

Aperçu rapide pour SLAMF1 anticorps (ABIN2658114)

Antigène: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp SLAMF1 est non-conjugé

Application: Multiplex Assay (MA)

Clone: TC15-12F12-2

Détail du produit anti-SLAMF1 anticorps

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2a lambda

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détails sur SLAMF1

Antigène: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Autre désignation: CD150

Sujet: CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.