Cet anticorps anti-PDCD1LG2 Monoclonal Souris conjugué à APC (Clone MIH18) (ABIN2658152) détecte spécifiquement PDCD1LG2 dans FACS.
L’anticorps est réactif avec des échantillons de Humain.
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Protect from prolonged exposure to light. Do not freeze.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C.
Antigène
PDCD1LG2
(Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
Autre désignation
CD273
Sujet
CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions. Clone MIH18 is reported to block PDL2.