Integrin alpha 1 anticorps (APC)

N° du produit ABIN2658243

Détail du produit anti-Integrin alpha 1 anticorps (APC)

Antigène: Integrin alpha 1 (ITGA1)

Reactivité: Souris

Hôte: Hamster arménien

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin alpha 1 est conjugé à/à la APC

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Clone: HMalpha1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur Integrin alpha 1

Antigène: Integrin alpha 1 (ITGA1)

Autre désignation: CD49a (ITGA1 Produits)

Synonymes: anticorps CD49A, anticorps E130012M19Rik, anticorps Vla1, anticorps CD49a, anticorps VLA1, anticorps integrin alpha 1, anticorps integrin subunit alpha 1, anticorps Itga1, anticorps ITGA1

Sujet: CD49a is a 1179 aa, type I transmembrane glycoprotein also known as α1 integrin, VLA-1 α chain, or integrin α1. It associates antibody v042010 with CD29 (β1 integrin) to form the VLA-1 complex, a collagen IV and alminin-1 receptor that is expressed on activated T cells, smooth muscle cells, endothelial cells, neuronal cells, fibroblasts, and mesenchymal cells. CD49a is an adhesion molecule and is involved in the regulation of leukocyte migration, T cell proliferation, and cytokine production.

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex