DLL4 anticorps (APC)

N° du produit ABIN2658301

L’anticorps Souris Monoclonal anti-DLL4 a été validé pour ICFC. Il convient pour détecter DLL4 dans des échantillons de Humain.

Aperçu rapide pour DLL4 anticorps (APC) (ABIN2658301)

Antigène: DLL4 (delta-Like 4 (DLL4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DLL4 est conjugé à/à la APC

Application: Intracellular Flow Cytometry (ICFC)

Clone: MHD4-46

Détail du produit anti-DLL4 anticorps (APC)

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur DLL4

Antigène: DLL4 (delta-Like 4 (DLL4))

Autre désignation: delta-Like Protein 4

Sujet: Delta-like protein 4 (DLL4) is a type I transmembrane protein whose extracellular domain contains a DSL domain and eight tandem EGF repeats. After binding of its ligands Notch 1 and Notch 4, the extracellular and cytoplasmic domains are cleaved and the cytoplasmic domain is translocated into the nucleus. DLL4 is expressed in the vascular endothelium, neural epithelium, adrenal cortex, spleen, and lymph nodes. It is also highly expressed in some types of bladder, breast, and renal carcinomas. DLL4 is critical in vascular development and homeostasis.

Pathways: Signalisation Notch