SIGLEC10 anticorps (APC)

N° du produit ABIN2658387

Cet anticorps Souris Monoclonal détecte spécifiquement SIGLEC10 dans FACS, IF et ICFC. Il présente une réactivité envers Humain.

Aperçu rapide pour SIGLEC10 anticorps (APC) (ABIN2658387)

Antigène: SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIGLEC10 est conjugé à/à la APC

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Intracellular Flow Cytometry (ICFC)

Clone: 5G6

Détail du produit anti-SIGLEC10 anticorps (APC)

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur SIGLEC10

Antigène: SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))

Autre désignation: Siglec-10

Sujet: Siglec-10 is a lectin that specifically binds α-2,3- or α-2,6-linked sialic acid. It is a member of the Ig-superfamily and is expressed in monocytes, eosinophils, B cells, and a subset of NK cells. Siglec-10 is a single pass transmembrane protein. The extracellular domain contains one V-set Ig-like domain and three C2-set domains, the cytoplasmic domain contains one immunoreceptor tyrosine-based inhibitor motif (ITIM) which, after tyrosine-phosphorylation, recruits SH2-family phosphatases such as SHP-1 and PTPN6, resulting in the blocking of the signal transduction. CD24 and the vascular adhesion protein-1 (VAP-1) have been described as ligands of Siglec-10.