Cet anticorps anti-CXCR5 Monoclonal Souris conjugué à PE-Dazzle™ 594 (Clone J252D4) (ABIN2659667) détecte spécifiquement CXCR5 dans FACS et CyTOF.
L’anticorps est réactif avec des échantillons de Humain.
The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions. The solution is free of unconjugated PE/Dazzle™ 594 and unconjugated antibody.
CD185, also known as CXCR5, is a 42 kD G-protein coupled receptor with seven transmembrane regions. CXCR5 is expressed by mature B cells, follicular helper T cells (TFH), Burkitt's lymphoma cells and a subset of neurons, and mediates cell migration to the B cell follicles in the secondary lymphoid organs. The ligand of CXCR5 is CXCL13 (BLC).