CD27 anticorps (PerCP)
Aperçu rapide pour CD27 anticorps (PerCP) (ABIN2659846)
Antigène
Voir toutes CD27 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Réactivité croisée
- Babouin, Cynomolgus, Macaque rhésus, Squirrel Monkey (Saimiri spec.)
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Purification
- The antibody was purified by affinity chromatography, and conjugated with PerCP under optimal conditions. The solution is free of unconjugated PerCP and unconjugated antibody.
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Isotype
- IgG1 kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Protect from prolonged exposure to light. Do not freeze.
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Stock
- 4 °C
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Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- CD27 (CD27 Molecule (CD27))
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Autre désignation
- CD27
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Sujet
- CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.
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Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Antigène
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