SLAMF1 anticorps (Biotin)

N° du produit ABIN2660951

Détail du produit anti-SLAMF1 anticorps (Biotin)

Antigène: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp SLAMF1 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

Clone: TC15-12F12-2

Isotype: IgG2a lambda

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur SLAMF1

Antigène: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Autre désignation: CD150 (SLAMF1 Produits)

Synonymes: anticorps CD150, anticorps SLAM, anticorps SLAMF1, anticorps 4933415F16, anticorps AA177906, anticorps CDw150, anticorps ESTM51, anticorps IPO-3, anticorps Slam, anticorps RGD1560634, anticorps signaling lymphocytic activation molecule family member 1, anticorps SLAMF1, anticorps Slamf1

Sujet: CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.