CD70 anticorps (Biotin)
Aperçu rapide pour CD70 anticorps (Biotin) (ABIN2661128)
Antigène
Voir toutes CD70 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
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Isotype
- IgG2b kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Do not freeze.
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Stock
- 4 °C
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Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- CD70 (CD70 Molecule (CD70))
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Autre désignation
- CD70
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Sujet
- CD70 is a type II transmembrane protein. It is a member of the TNF superfamily, expressed on activated B cells, activated dendritic cells, and some activated T cells (low levels). CD70 interacts with CD27 to promote T-B cell cross-stimulation and co-stimulate B cell proliferation and immunoglobulin production. Cells expressing CD70 can co-stimulate T cell proliferation and enhance the production of cytokines. The FR70 antibody blocks CD70 binding to CD27.
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Pathways
- Cancer Immune Checkpoints
Antigène
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