IL-5 anticorps (Biotin)

N° du produit ABIN2661236

Cet anticorps anti-IL-5 est un anticorps Rat Monoclonal détectant IL-5 dans FACS. Adapté pour Souris.

Aperçu rapide pour IL-5 anticorps (Biotin) (ABIN2661236)

Antigène: IL-5 (IL5) (Interleukin 5 (IL5))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-5 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: TRFK4

Détail du produit anti-IL-5 anticorps (Biotin)

Purification: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

Isotype: IgG2a, IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur IL-5

Antigène: IL-5 (IL5) (Interleukin 5 (IL5))

Autre désignation: IL-5

Sujet: IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. The native protein can have variable molecular weight as a result of glycosylation. Monomeric mouse IL-5 is a 113 amino acid protein with a reported molecular weight of 35-37 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70 % identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors and stimulates the activation, and differentiation of eosinophils, and promotes the generation of cytotoxic lymphocytes . Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK4 antibody reacts with mouse interleukin-5 (IL-5). The TRFK4 antibody can neutralize the bioactivity of natural or recombinant IL-5.

Pathways: Signalistation JAK/STAT, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour