CCRL2 anticorps (PE)

N° du produit ABIN2662410

Détail du produit anti-CCRL2 anticorps (PE)

Antigène: CCRL2 (Chemokine (C-C Motif) Receptor-Like 2 (CCRL2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCRL2 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: K097F7

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CCRL2

Antigène: CCRL2 (Chemokine (C-C Motif) Receptor-Like 2 (CCRL2))

Autre désignation: CCRL2 (CCRL2 Produits)

Synonymes: anticorps CCRL2, anticorps ACKR5, anticorps CKRX, anticorps CRAM, anticorps CRAM-A, anticorps CRAM-B, anticorps HCR, anticorps 1810047I05Rik, anticorps Ackr5, anticorps CCR11, anticorps Cmkbr1l2, anticorps E01, anticorps L-CCR, anticorps C-C motif chemokine receptor like 2, anticorps chemokine (C-C motif) receptor-like 2, anticorps Ccrl2, anticorps CCRL2

Sujet: CCRL2 (C-C chemokine receptor-like 2) is a seven transmembrane, G-protein coupled receptor with two isoforms generated from alternative splicing. CCRL2 is expressed by the majority of cell types of hematopoietic origin, including monocytes, macrophages, neutrophils, lymphocytes, and NK cells. In some cell types, its expression is upregulated by inflammatory stimuli. CCRL2 is important for the development of Th2 responses and may act as a decoy receptor capturing and endocyting its ligands CCL5 and CCL19, however, it has been found that CCRL2 captures and retains chemerin/RARRES2 on its cell surface, presenting it to neighboring cells.