LTBR anticorps (PE)
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- Antigène Voir toutes LTBR Anticorps
- LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp LTBR est conjugé à/à la PE
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Purification
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- Clone
- 31G4D8
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product LTBR Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from prolonged exposure to light. Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Antigène
- LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))
- Autre désignation
- Lymphotoxin beta Receptor (LTBR Produits)
- Synonymes
- anticorps AI256028, anticorps CD18, anticorps LTbetaR, anticorps Ltar, anticorps TNF-R-III, anticorps TNFCR, anticorps TNFR-RP, anticorps TNFR2-RP, anticorps TNFRrp, anticorps Tnfbr, anticorps Tnfrsf3, anticorps D12S370, anticorps LT-BETA-R, anticorps TNFR3, anticorps TNFRSF3, anticorps lymphotoxin beta receptor, anticorps lymphotoxin B receptor, anticorps Ltbr, anticorps LTBR
- Sujet
- LT-βR, also known as lymphotoxin beta receptor and tumor necrosis factor receptor superfamily member 3 is a 47 kD transmembrane protein containing 3 TNF receptor domains. The LT-βR is a receptor for the heterotrimeric lymphotoxin complex (composed of LTα and LTβ as well as LIGHT). LT-βR is highly expressed in the lung, liver, and kidney and moderately expressed expressed in the heart and testes. LT-βR is weakly expressed in the brain, thymus, spleen, and lymph nodes. The cytoplasmic tail of LT-βR interacts with TRAF3, TRAF4, and TRAF5 as well as the hepatitis C virus core protein. Ligand binding to LT-βR has been shown to induce apoptosis (via TRAF3 and TRAF5) and play a role in the development of lymphoid organs. The 31G4D8 antibody has been shown to be useful for flow cytometry, Western blot, immunoprepicitation and and ELISA (detection antibody). In addition, the 31G4D8 antibody is an agonistic antibody for the LT-βR capable of inducing apoptosis (with IFN-γ treatment).
- Pathways
- Signalisation NF-kappaB
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