Cet anticorps anti-C3AR1 Monoclonal Souris (Clone hC3aRZ8) (ABIN2664086) détecte spécifiquement C3AR1 dans FACS et IHC.
L’anticorps est réactif avec des échantillons de Humain.
C3AR is a single chain protein of 482 aa, with seven membrane-spanning regions and a molecular weight of 54 Kd. C3AR is expressed by neutrophils, eosinophils, mast cells, monocytes, dendritic cells and there are reports of C3AR expression in non-immune cells such as hematopoietic and mesenchymal stem cells, epithelial and endothelial cells. C3AR is coupled to heterotrimeric G proteins and after C3a binding, the signal transduced, results in chemotaxis, granule enzyme release and superoxide anion production.