CCRL2 anticorps

N° du produit ABIN2664102

Cet anticorps Souris Monoclonal détecte spécifiquement CCRL2 dans IHC et ELISA (Capture). Il présente une réactivité envers Humain.

Aperçu rapide pour CCRL2 anticorps (ABIN2664102)

Antigène: CCRL2 (Chemokine (C-C Motif) Receptor-Like 2 (CCRL2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCRL2 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA (Capture)

Clone: K097F7

Détail du produit anti-CCRL2 anticorps

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CCRL2

Antigène: CCRL2 (Chemokine (C-C Motif) Receptor-Like 2 (CCRL2))

Autre désignation: CCRL2

Sujet: CCRL2 (C-C chemokine receptor-like 2) is a seven transmembrane, G-protein coupled receptor with two isoforms generated from alternative splicing. CCRL2 is expressed by the majority of cell types of hematopoietic origin, including monocytes, macrophages, neutrophils, lymphocytes, and NK cells. In some cell types, its expression is upregulated by inflammatory stimuli. CCRL2 is important for the development of Th2 responses and may act as a decoy receptor capturing and endocyting its ligands CCL5 and CCL19, however, it has been found that CCRL2 captures and retains chemerin/RARRES2 on its cell surface, presenting it to neighboring cells.