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IL7R anticorps

IL7R Reactivité: Humain DNA Mic, MA Hôte: Souris Monoclonal A019D5 unconjugated
N° du produit ABIN2664189
  • Antigène Voir toutes IL7R Anticorps
    IL7R (Interleukin 7 Receptor (IL7R))
    Reactivité
    • 121
    • 67
    • 26
    • 7
    • 4
    • 2
    • 1
    Humain
    Hôte
    • 81
    • 47
    • 45
    • 1
    • 1
    Souris
    Clonalité
    • 92
    • 81
    • 2
    Monoclonal
    Conjugué
    • 68
    • 13
    • 13
    • 11
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL7R est non-conjugé
    Application
    • 96
    • 84
    • 48
    • 26
    • 26
    • 20
    • 14
    • 13
    • 10
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    DNA Microscopy (DNA Mic), Multiplex Assay (MA)
    Purification
    The antibody was purified by affinity chromatography.
    Clone
    A019D5
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product IL7R Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Antigène
    IL7R (Interleukin 7 Receptor (IL7R))
    Autre désignation
    CD127 (IL7R Produits)
    Synonymes
    anticorps IL7R, anticorps CD127, anticorps IL-7Ralpha, anticorps CDW127, anticorps IL-7R-alpha, anticorps IL7RA, anticorps ILRA, anticorps IL-7RA, anticorps interleukin 7 receptor, anticorps IL7R, anticorps Il7r
    Sujet
    CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.
    Pathways
    Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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