Cadherin 5 anticorps

N° du produit ABIN2664234

Détail du produit anti-Cadherin 5 anticorps

Antigène: Cadherin 5 (CDH5)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cadherin 5 est non-conjugé

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography.

Clone: BV9

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur Cadherin 5

Antigène: Cadherin 5 (CDH5)

Autre désignation: CD144 (CDH5 Produits)

Synonymes: anticorps 7B4, anticorps AA408225, anticorps Cd144, anticorps VE-Cad, anticorps VECD, anticorps VEcad, anticorps Vec, anticorps wu:fc88a07, anticorps CD144, anticorps cadherin-5, anticorps cadherin 5, anticorps CDH5, anticorps Cdh5, anticorps cdh5

Sujet: CD144, also known as VE-cadherin and cadherin-5, is a 140 kD glycoprotein which is composed of five extracellular cadherin repeats and a highly conserved cytoplasmic tail region. It is a calcium-dependent transmembrane cell-cell adhesion molecule localized at the intercellular boundaries of endothelial cells, hematopoietic stem cells, and perineurial cells. It functions as a classic cadherin by mediating homophilic adhesion and functions as a plasma membrane attachment site for the cytoskeleton. CD144 is thought to play a role in vascular development, permeability, and remodeling.

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2