DDR1 anticorps

N° du produit ABIN2664284

Détail du produit anti-DDR1 anticorps

Antigène: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DDR1 est non-conjugé

Application: Flow Cytometry (FACS)

Attributs du produit: The 51D6 monclonal antibody recognizes human CD167a also known as discoidin domain receptor, DDR1, neuroepithelial tyrosine kinase, epithelial-specific receptor kinase, tyrosine kinase receptor E (trkE), cell adhesion kinase (CAK), PTK3, and RTK6. CD167a is a membrane type II receptor kinase, containing a factor VIII-like domain. At least five isoforms are generated through alternative splicing of the kinase domain of human DDR1 gene. These isoforms are named with suffixes a to e. CD167a is expressed on epithelial cells, keratinocytes, leukocytes, monocytes and has been reported to be overexpressed in some breast carcinomas. CD167a expression can be upregulated by p53. CD167a has been reported to interact with a variety of proteins including collagen type II alpha 1, collagen type III alpha 1, collagen type V alpha 2, collagen type XI alpha 1, phospholipase gamma 1, SHC, and the lipid-anchored docking protein FRS2. CD167a can be phosphorylated on Y513. Animal studies suggest that CD167a is involved in arterial wound healing. The 51D6 antibody has been shown to be useful for flow cytometric detection of human CD167a as well as immunoprecipitation.

Purification: The antibody was purified by affinity chromatography.

Clone: 51D6

Isotype: IgG3 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur DDR1

Antigène: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Autre désignation: CD167a (DDR1 Produits)

Synonymes: anticorps CG11573, anticorps CG13984, anticorps CG13985, anticorps CG33531, anticorps CG9488, anticorps CG9490, anticorps CT33540, anticorps DDR, anticorps Dmel\\CG33531, anticorps Dmel_CG13984, anticorps 6030432F18, anticorps AI323681, anticorps CD167a, anticorps Cak, anticorps Nep, anticorps PTK3A, anticorps CAK, anticorps CD167, anticorps EDDR1, anticorps HGK2, anticorps MCK10, anticorps NEP, anticorps NTRK4, anticorps PTK3, anticorps RTK6, anticorps TRKE, anticorps Drd1, anticorps PTK3D, anticorps Discoidin domain receptor, anticorps discoidin domain receptor family, member 1, anticorps discoidin domain receptor tyrosine kinase 1, anticorps Ddr, anticorps Ddr1, anticorps DDR1

Pathways: Signalisation RTK, Smooth Muscle Cell Migration